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This metabolic reprogramming enhances fatigue resistance and recovery capacity by improving the efficiency of energy production from aerobic pathways

PMID: 28446493, PMCID: PMC5524055, DOI: 10.1161/jaha.116.004276

Joint and connective tissue support: TRT increases muscle strength, which can place additional stress on joints and tendons

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Patients with Renal Impairment Dapagliflozin At steady-state (20 mg once daily dapagliflozin for 7 days), adult patients with type 2 diabetes mellitus with mild, moderate, or severe renal impairment (as determined by eGFR) had geometric mean systemic exposures of dapagliflozin that were 45%, 100% and 200% higher, respectively, as compared to patients with type 2 diabetes mellitus with normal renal function