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Most approved antibodies are built on full-length IgG1, and the constant IgG1 Fc region is also used as a fusion partner to extend the plasma half-life of fused therapeutic modalities 12

[27] Yago MR, Frymoyer AR, Smelick GS, et al

Journal Of Biomolecular Structure & Dynamics, 42 (10), 5015-5029

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Secondly, by initiating the program with many different initial conditions, we consistently arrived at the same periodic solution after a few months