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If you are not planning a pregnancy, ensure you are using effective contraception

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The good news is that as semaglutide improves glycemic control over time, the diabetes-related UTI risk factors may actually decrease

The glucose-dependent insulinotropic polypeptide receptor adds a second layer of metabolic regulation that amplifies fat oxidation, improves lipid metabolism, and appears to enhance the weight loss effects beyond what GLP-1 activation alone can achieve

Patients with genetic markers suggesting lower muscle preservation efficiency may benefit from higher baseline protein intake (1.3+ grams per kilogram) or earlier introduction of resistance training

This approach allows your body to adjust and helps reduce side effects like nausea and other stomach issues