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Subcutaneous fat is more directly measurable but less metabolically active, so peptide studies on it tend to use different endpoints than those used in visceral-fat-focused research

They are primarily used to treat various forms of hypothyroidism, including post-thyroidectomy replacement, congenital thyroid hormone deficiency, and situations where levothyroxine monotherapy fails to relieve symptoms

Armour, M., Sinclair, J., Chalmers, K

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