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The principle behind the leaky gut theory is that endogenous (e.g., psychological stress, intestinal inflammation) and exogenous factors (e.g., diet, alcohol intake) can increase intestinal permeability, allowing the entrance of food antigens, commensal or pathogenic bacteria and bacterial components into the lamina propria and later on into the systemic circulation, provoking the systemic inflammation described in different disease conditions

The IRs of anaphylaxis observed in this study are also consistent with prior observational evidence, including the cohort study by Pradhan et al

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Standard prenatal supplements containing iodine may be appropriate for those with insufficient dietary intake

An increase in probiotic Bifidobacterium was detected in all donors (Jimnez-Arroyo et al., 2023)