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This trial set the standard for anti-obesity incretin mimetics and launched the commercialization of Wegovy

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The effect of combining GLP-1RAs with other drugs (e.g., biologics) for the treatment of IBD can be explored in the future

Current evidence suggests that ispaghula husk may contribute to a modest enhancement of endogenous GLP-1 secretion , likely mediated through viscosity effects, delayed gastric emptying, and possibly some SCFA production

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