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Journal of Clinical Neurology

Journal of Alzheimers Disease , 2025

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It regulates: Energy homeostasis , complementarily to MC4R but via different pathways Anti-inflammatory effects in macrophages Sebaceous glands (partially) Activation of MC3R contributes to the metabolic and anti-inflammatory effects of Melanotan II, but is less characterized than MC4R

This double mutant was substantially more active on diphenols than Asn240Lys/Leu244Arg, which was demonstrated by the k cat value for dopamine, which was 27-fold increased

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