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Brain-Derived Neurotrophic Factor BDNF Supports neurological function, cognitive performance and healthy brain activity

showed that FOXO4 expression is upregulated in irradiated-induced senescent IMR90 cells and that the protein binds to p53, inhibiting the role of this last one in apoptosis induction

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Pickart (2008) reviewed the broader tissue remodeling context and argued that GHK operates as a damage signal released from injured or aging tissue, recruiting repair processes that decline as the signal itself becomes less abundant

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