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Summary: For most people requiring oral supplementation, cyanocobalamin is the most commonly used and effective form of B12, whilst hydroxocobalamin injections are the preferred treatment for confirmed deficiency in UK clinical practice

The latter is better, but we recommend methylcobalamin, as it includes a methyl group and directly aids in lowering homocysteine levels and in fixing nerve damage, two issues often faced by pernicious anemia and B12 deficiency patients

Side effects are rare, but you might experience mild tenderness at the site, like any injection

It thus provides good information about the supply

Followed by weekly, then monthly maintenance doses

Two trials reported data for serum vitamin B 12 levels