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Studies distinguishing between e-cigarettes with and without nicotine found increases in endothelial progenitor cells, endothelial vesicles, plasma myeloperoxidase, arterial stiffness, changes in nicotine receptors, alveolar macrophages, and mononuclear phagocytes, leading to altered inflammatory responses and increased pulmonary susceptibility in users of nicotine-containing e-cigarettes (29, 41, 46)

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Moroz I, Scapolio LGB, Cesarino I, Leo AL, Bonanomi G (2021) Toxicity of cigarette butts and possible recycling solutionsa literature review