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They are particularly apt as an in vitro study model in regenerative medicine and in systemic diseases [19,20]

It is difficult for morphine to impel the internalization of desensitized MOR, and the latter cannot be dephosphorylated within the cell [88], so repeated morphine treatment leads to the accumulation of desensitized MORs, representing the downregulation of functional MOR and ultimately leading to tolerance

ElSayed NA et al (2023) 11

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Residents seeking authentic results are turning to IV and injectable treatments for their clinically proven benefits

Risk of hepatic events associated with use of sodium-glucose cotransporter-2 inhibitors versus glucagon-like peptide-1 receptor agonists, and thiazolidinediones among patients with metabolic dysfunction-associated steatotic liver disease