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In those with coeliac disease, the potential of developing a leaky gut is greater

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A growing body of evidence has shown that metals (including heavy metals) are able to generate ROS, which subsequently can lead to lipid peroxidation, thereby causing damage to DNA, as well as the consumption and eventual depletion of a cells antioxidant defence mechanisms

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Associated cardiometabolic abnormalities include central obesity, insulin resistance, dyslipidemia, and systemic inflammation