Local reactions may include erythema, pruritus, induration, or mild pain at the injection site, potentially affecting five to ten percent of patients
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The manufacturer recommends to give 1 mL by mouth per day for cats and small dogs, 2 mL by mouth per day for medium sized dogs (25-50 lbs), and 3 mL by mouth per day for large sized dogs (50-100 lbs)
To minimize risk and protect patients, while still providing for their clinical need, the Drug Quality and Security Act was signed into law and a new section was added under the Federal Food, Drug, and Cosmetic Act
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Local Coverage Determination Reference The Centers for Medicare & Medicaid Services (CMS) local coverage determination remains the authoritative source for Part B criteria regarding B12 injections