The peptide also potentially maintains spindle integrity and the correct distribution of cortical granules (CG)
Neurobiol Aging 51:104112
doi:10.3390/ph16030185
Intramuscular hydroxocobalamin injections represent the standard treatment for most cases: Initial loading regimen : For patients with neurological symptoms, 1 mg on alternate days until no further improvement occurs (typically 23 weeks)

Across dozens of studies, daily astaxanthin doses between 4mg and 12mg have been linked to improvements in skin hydration, elasticity, and UV resilience, as well as benefits for eye comfort, exercise recovery, and cognitive performance.1 2 3 5 6 Lower doses (46mg per day) often support skin and eye outcomes, but research suggests 12mg daily may unlock even broader effects.1 7 13 At 12mg, trials show improved endurance performance including faster cycling time trials and reduced muscle-soreness markers.3 8 Other studies point to enhanced cognitive function and sleep quality, benefits that tend to appear near the upper end of the dosing range.4 9 Taken together, these findings helped establish 12mg per day as the most compelling astaxanthin dose in the scientific literature
A B12 injection delivers a concentrated dose of vitamin B12 into the muscle for a fast energy and mood boost, while IV therapy infuses a broader blend of vitamins, minerals, and hydration directly into your bloodstream