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This peptide hormone regulates calcium homeostasis and bone metabolism, addressing the underlying pathophysiology of these bone disorders

PMID: 18177285

The GSH synthesis genes gshA and gshB could be used in the synthesis process of EGT, at the same time, EGT could also promote the synthesis of GSH through the Nrf2/ARE pathway ( Actinobacteria , Mycobacterium , are also present in large quantities in the intestinal tract, EGT synthesis has never been found in animals

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In addition to participating in Fenton reactions, iron plays roles in other cellular metabolic pathways, such as by being transported to the mitochondria for the synthesis of heme or iron-sulfur (Fe-S) clusters