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Some users stack tirzepatide with other peptides like BPC-157 for gut health, ipamorelin for growth hormone support, or sermorelin for recovery
It binds both receptors but produces a stronger functional response at GIPR than at GLP-1R compared with the native ligands, which is part of why it behaves differently from a balanced co-agonist
Females of reproductive potential should use adequate contraception while taking this medication
The body naturally produces these hormones for a short time after a person eats, but by introducing them artificially with these medications, food moves more slowly through the body and keeps people feeling full, longer
These studies measured weight reduction over a 72-week period (about a year and a half)