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What's very clear, however, is that what we consume on a regular basis and what leads to increases in brain metabolism leads to increases in dopamine, and thereby our motivation to eat them

This effect was fully suppressed by the microglial inhibitor minocycline and the p38 mitogen-activated protein kinase (MAPK) inhibitor SB203580, underscoring the essential role of microglial activation and the p38 MAPK pathway [72]

Mood and anxiety disorders Pre-clinical and mechanistic studies Articles relevant to this section mainly addressed depressive and anxiety conditions, while only two pre-clinical studies investigated the effect of GLP-1RAs in bipolar disorder (Supplementary Section 5)

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Colloton M, Shatzen E, Miller G, Stehman-Breen C, Wada M, Lacey D, Martin D