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Introduction Amyotrophic Lateral Sclerosis (ALS) is a heterogeneous neurodegenerative disease that primarily affects both upper and lower motor neurons, leading to their progressive degeneration and subsequent, often rapid loss of motor function and death (Brotman et al., 2022)

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CJC-1295 Without DAC (Modified GRF 1-29) + Ipamorelin is a synergistic dual-peptide combination of a GHRH analogue and a selective GH secretagogue, available to buy in Europe for laboratory research into growth hormone pulse physiology, GHRH/GHRP synergy mechanisms, somatotroph biology, GH axis pharmacology, and the comparative study of pulsatile versus tonic GH secretion patterns