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Moreover, acetylcarnitine is rapidly metabolized in the gut by microbiota to trimethylamine, which is further metabolized in the liver to trimethylamine N-oxide, a biomarker of cardiometabolic risk [28]

Previously, we demonstrated that CAV-1 reduction increased STAT3 phosphorylation in human keratinocytes and that CSD reduced the number of pSTAT3-positive cells in the epidermis of mice with IMQ-induced psoriasis-like inflammation 6

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