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This risk is particularly pronounced in individuals with a history of substance abuse

[3] [4] Improved diabetes control achieved through Ozempic treatment might be expected to enhance rather than impair sexual function over time

Some people experience reduced effectiveness over time , but this is related to metabolic adaptation and dose adequacy, not injection timing

trial product estimand) and -21 percentage points with semaglutide 20 mg and -19 percentage points with semaglutide 10 mg (ETD -018 percentage points [-031 to -004]