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In addition to increased transcription of NRF2 target genes, livers from Gclc KO mice had lower expression of lipogenic genes and proteins (Fig

Participants were evaluated using the Pervasive Developmental Disorders Behavioral Inventory (PDDBI), BASC-2, CGI-I, VABS-II, and Preschool Language Scale (PLS-4), however, none of them evidenced a statistically significant effect in ASD symptoms

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Slower transit may also prolong nutrient contact with distal L-cells, potentially amplifying the secretion of beneficial hormones like GLP-1, which enhances insulin secretion and further suppresses appetite (98, 99)