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Bosco DA, Fowler DM, Zhang Q, Nieva J, Powers ET, Wentworth P, et al

In 2021, semaglutides weight-loss brand Wegovy (weekly injectable) was approved for obesity, followed by tirzepatide (Mounjaro) for diabetes (2022) and Zepbound (tirzepatide for obesity) in late 2023

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Hereon the review will focus on PKC properties in general, and refer to specific PKC isoforms when appropriate, such as the predominantly brain-expressed PRKCG

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