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Natural activation and pharmaceutical GLP-1 agonists work through fundamentally different mechanisms and shouldnt be directly compared on effectiveness alone

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Long-term sustainability depends on continuing treatment, as weight typically returns when GLP-1 medications are discontinued

S-acetyl L-glutathione , once inside the cells, can be readily converted to reduced glutathione, potentially offering a more efficient way to increase intracellular glutathione levels

doi:10.3389/fendo.2023.1215356 Parker CH, Slattery C, Brennan DJ, le Roux CW

Aim of the study We present a large series of OM with analysis of demographics, clinical appearance, histologic presentation, and review of the literature