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Together, these ingredients help to gently exfoliate, brighten the complexion, and improve skin texture

RCT, randomized controlled trial

Gorbatenko VO, Goriainov SV, Babenko VA et al (2022) Anti-inflammatory properties of metformin during cultivation of primary rat astrocytes in a medium with high glucose concentration

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On the other hand, it regulates the balance of iron and copper ion metabolism, inhibiting the occurrence of ferroptosis and cuproptosis and balancing proinflammatory and anti-inflammatory responses

Additionally, the loss of the transcription factor CBF in tumor cells disrupts zinc homeostasis pathways, further impairing their responsiveness to TNF-dependent cytotoxicity [329]