Importantly, most patients experience significant improvement within 4-8 weeks as their digestive system adapts
alternatives include SGLT2 inhibitors, DPP-4 inhibitors, insulin, or specialist allergy assessment for switching agents
77,78 However, the results of blinded studies have not been as promising
Others echo these experiences , highlighting reduced joint pain, better gut health, and quicker bounce-back from injuries
If that argument implicitly limited the claim to excipients not disclosed in the prior art, a generic manufacturer using a different excipient may be able to design around the patent without triggering literal infringement, and prosecution history estoppel may prevent the infringement claim based on equivalents
Furthermore, DPP4 is not just a cell membrane protein but is shed into the circulation as soluble DPP4