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Advantage: Potential for higher bioavailability than standard oral ingestion Challenge: Peptides are poorly absorbed through intact mucosal membranes without transport mechanisms Evidence: No studies confirm enhanced sublingual bioavailability for Dihexa Standard oral (swallowed): Tablets swallowed with water, absorbed through the gastrointestinal tract

(accessed May 2013) 58.Merck Sharp & Dohme Corp

10.1042/BJ20110009 62

Each mouse was euthanized, and their entire brain was removed and liquified to use as a single sample

Primary cultures for pancreatic stellate cells (PSCs)

Ashley Koff, RD 00:32:06 So a couple of thoughts here