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of those smoking up to a pack a day, 34 will not live to 65, and of those smoking two packs a day or more, 41 will die before 65. Wallace said statistics show smokers who quit move into a lower mortality rate, but never back to the original non-smoker level

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(See Figure 1.) This continuum of risk creates a significant harm-reduction opportunity for people who continue to use nicotine or who take up nicotine and otherwise would smoke

findings have also highlighted the adverse impact of tobacco smoke on male fertility (Sharma et al