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Directly after baseline breath assessment and under the supervision of a technician, CSs smoked 8 puffs of the supplied cigarette and ECs consumed 8 puffs of the supplied e-cigarette

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In its final rule, CTP provides information on the types of investigations that applicants must submit as part of a PMTA, if published, known to, or which should reasonably be known to an applicant including, but not limited to, genotoxicity, carcinogenicity, respiratory toxicity, cardiac toxicity, reproductive and developmental toxicity, and chronic (repeated dose) toxicity of the new TNCP relative to other TNCPs