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A 2024 paper in Physiology & Behavior characterised that ipamorelin and the related GHSR-1a agonist anamorelin inhibited cisplatin-induced weight loss in ferrets, framing one route by which the GHSR-1a agonist class engages cachexia research (PMID 39043357)

Regression Analysis of Gastric Volume in GLP-1 RA Users Without Solid Content Analyses of gastric volume (GV) were restricted to GLP-1 RA users without retained solids (n = 70)

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Therefore, it appears that some other circulating factor that is released during AOM-induced hepatotoxicity contributes to increased BBB permeability observed following AOM treatment

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Understanding epigenetic mechanisms opens new therapeutic possibilities