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Following the remodelling phase, a higher proportion of synthesised type I collagen, a corresponding decrease in cellularity, glycosaminoglycan content and type III collagen (Sharma and Maffulli 2005) can be observed

PubChem compound summary for CID 1880, 7,8-dihydroxyflavone

Cell 2013;152:117383

A subsequent 24-week Phase IIb study with 536 subjects found no statistically significant weight-loss difference , leading to termination of development in 2007

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It may also encourage collagen synthesis , which is vital for the integrity of muscles, tendons, and ligaments