By selectively recruiting LXR coregulators, GF2 reduces hepatic lipid accumulation and suppresses inflammation of identify GF2 as a promising therapeutic candidate for metabolic liver diseases (8587)
The mitochondrial metabolism of reactive oxygen species also requires the use of glutathione (Won et al., 2015)
Kassir R, Kolluru A, Kassir M (2011) Intense pulsed light for the treatment of rosacea and telangiectasias
In this context, zinc plays a crucial role promoting the tolerogenic phenotype in DCs and suppressing pro-inflammatory responses, thereby helping to restore a balance that is critical in aging immune systems [263, 264]
Proc Natl Acad Sci USA 105(28):98419846
Additionally, using SIRT1 knockout mice and STAT3 knockout mouse models may provide more conclusive insights into GHKs mechanism of action