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An increased concentration of cAMP leads to the activation of protein kinase A (PKA), which activates tissue-specific downstream signaling pathways ( functional antagonism of the GIP receptor ( Figure 2C )

(2014) Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: 1-D1-H3 receptor complexes as key targets for reducing cocaines effects

Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473

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