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This gap is especially pronounced for musculoskeletal end points such as tendon-to-bone healing and cartilage repair

K-means clustering of amplicon sequence variant data confirmed that 5-Amino-1MQ treatment generated a distinct cecal microbiome profile from all other treatment groups including diet-switched vehicle controls indicating that NNMT inhibition produces microbiome changes that are separable from those produced by dietary composition alone

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Can be taken with or without food