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Additionally, catalpol activates the Osteopontin/phosphorylation-insulin-like growth factor 1 receptor (p-IGFR)/mTOR signaling axis, promoting the vitality, migration, and axonal growth of SH-SY5Y cells following OGD/reoxygenation injury, contributing to neuronal protection, nerve cell migration, and axonal regeneration under ischemic and hypoxic conditions (Liu Y

PMCID: PMC11646169

doi: 10.1016/j.molmet.2018.05.012 15 TumminiaAVinciguerraFParisiMFrittittaL

Age-related cognitive decline may be associated with reduced oxytocin levels, as this hormone influences multiple areas of the brain and could be a critical element that diminishes with age