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In CF animal models, increased TBARS have been demonstrated in the lung tissue of Cftr -KO mice, reflecting localized oxidative damage within affected organs (Velsor et al., 2001), although TBARS in BAL fluid (BALF) were below detection limits in both Cftr -KO and WT mice

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Treat biological-age scores as exploratory, and keep standard preventive care, physical function, sleep, nutrition, blood pressure, and healthcare-provider review at the center of the plan

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