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Sulfonylureas [35], which lower blood glucose by stimulating insulin secretion, and thiazolidinediones [36], which act as insulin sensitizers by binding to PPAR- receptors, are similarly not commonly associated with intestinal obstruction

Other mechanisms such as VPA-induced lipid peroxidation and glutathione depletion could also contribute to hepatotoxicity [59]

Much of this research tends to focus on women, but stress management is a tool shown to increase male fertility

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