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Figure 3 shows the HPLC detection spectrum of His racemization impurities produced by His coupling during the preparation of Semaglutide in Example 10

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Conclusin : Los parches de GLP-1 pueden contener ingredientes reconocibles, pero actualmente no hay pruebas slidas de que esos ingredientes se absorban a travs de la piel en cantidades suficientes para respaldar los efectos que se afirman

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