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The approval was supported by data from the Phase III PRECISION trial, where both the 12.5-mg and 25-mg dose levels of Tryvio significantly reduced sitting systolic blood pressure compared with placebo after four weeks of treatment

(2017) 25:107590.e5

FSAs follow IRS rules that focus on medical necessity

GLP-1 receptor agonists are having a moment

Inability to Demonstrate Value: In a world demanding transparency, a PBM that cannot provide its clients with clear, auditable data demonstrating that its services are leading to a lower total cost of care will face high rates of client churn

It's often used to enhance weight-loss efforts and boost metabolic function, though evidence for isolated weight-loss benefit is limited