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The need for the cycle between methionine and homocysteine to function in a repetitive fashion is illustrated by the fact that in men the homocysteine moiety is recycled between methionine and homocysteine twice before being converted to cystathionine, but in women it is recycled about 1.5 times (Chiang)

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The strength and significance of associations were further evaluated using Pearsons chi-square test and corresponding odds ratios, implemented with scipy.stats.chi2_contingency in Python 3.9.16

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