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However, erythrocytes of newborns are resistant to various triggers of eryptosis, but they are highly susceptible to oxidative stress and eryptosis, so after birth, replacement of fetal hemoglobin with adult hemoglobin is functionally essential [212]

Specific food components act as potent epigenetic modulators that can dynamically regulate gene expression

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Genetic backgrounds may also influence patients responses to specific drugs, with certain genetic variations potentially leading to differences in sensitivity to DMARDs or biologic agents