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Thyroid dysfunction, low testosterone, perimenopause, and elevated cortisol all directly undermine weight loss results and patients who succeed on GLP-1 therapy without addressing these underlying imbalances frequently regain weight when tapering off

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Understanding the distinction between medication effects and underlying disease risk is essential for informed decision-making

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Rising drug budgets are tightening formularies and prior authorization processes, as overall prescription drug spending is expected to increase by 9.0-11.0% in 2025

For patients receiving WEGOVY for CV risk reduction or weight reduction, discontinue WEGOVY when pregnancy is recognized