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SHARPIN promotes cell proliferation of cholangiocarcinoma and inhibits ferroptosis via p53/SLC7A11/GPX4 signaling

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A small number of ifosfamidetreated patients (up to 30%) develop acute encephalopathy within hours or days after administration, with dyskinesia, extrapyramidal syndromes, ataxia, myoclonus, and complex partial status epilepticus observed [165], mainly through mitochondrial toxicity and oxidative stress [166]